Pull a flower off of the pollen donor plant as soon as the anther is laden with pollen.
Remove the petals from the flower to expose the pollen-covered anther on top of the long, slender stigma. Pull off the stamen and anther.
Rub the anther's pollen on the receptor flower's stigma as soon as it becomes sticky. The stigma is the bumpy, rough protrusion in the exact center of the flower. If the stigma is not accessible, remove the flower's petals to reveal it.
Tape the receptor flower's petals closed (If present. If not, tape a small bag over the exposed stigma)if present) if the succulent is growing outside. This will prevent cross pollination by insects. If the flower is indoors where no insects can access it, there's no need to tape the flower closed. Mark the flower you pollinated by writing on the tape or a tag. If the pollination is successful, the base of the flower will swell in a few weeks to a few months depending on the succulent.
Collect the seeds in fall once they mature.