Allow the soil to dry to a depth of 4 inches before watering it. As a rule of thumb, hydrangeas require a deep watering once a week. Water every four-to-seven days during periods of drought.
Wait 10 days after the first watering after the wilting to fertilize. Use 20-20-20, at the dilution rate suggested on the label, and use it in place of plain water every third time you irrigate the hydrangea. This should help perk it up.
Take action immediately if the hydrangea's leaves and shoots wilt suddenly, despite proper watering. This is an early symptom of mushroom root rot, a fungal disease. There is no fungicide to manage mushroom root rot, so remove and destroy the hydrangea. Do not replant in the same soil.