Select a pot 2 inches wider and the same depth or slightly deeper than the current pothos container. Only use pots with bottom drainage holes so excess moisture can easily drain from the soil.
Fill the new pot one-third full with a peat-based potting soil. Water the soil until moisture begins to drain from the pot and until the soil becomes evenly moist throughout.
Turn the pothos pot on its side and place your hand over the top of the soil to support the plant. Tip it upside down and thunk the sides and bottom of the pot to loosen the soil so the pothos slides out of the pot.
Cut off any dark roots that are soft, smell bad or appear rotten, using a clean knife. Set the pothos in the prepared pot. Add more soil beneath the root ball, if necessary, so the top of the root ball sits 2 inches beneath the pot rim. Add soil around the roots until the pothos is planted at the same depth it was growing at in its old pot.
Water the transplanted pothos until moisture drips from the bottom and the soil settles around the roots. Set the pot in an area that receives all-day bright but indirect sunlight, and continue to water when the soil surface dries.