Place your pothos on a south- or west-facing windowsill that receives bright, indirect sunshine. While it will grow in low light, pothos vines produce larger, more colorful leaves if they get plenty of light. Keep the temperature between 70 and 90 degrees Fahrenheit for optimum growth.
Water when the surface of the soil is dry to the touch. Provide enough water to moisten the soil thoroughly but never leave pothos standing in water as this can cause root rot.
Fertilize every month during the warmer months of the year with a liquid houseplant fertilizer diluted by 50 percent. Fertilize every six weeks during the winter when growth is slower.
Repot your pothos into a larger container when its roots emerge through the drainage hole in its container. Use a free-draining compost based on peat. Provide your pothos with a moss pole or other structure to climb. Pothos plants only produce large leaves if they are able to climb upwards. Given a support structure, pothos vines can grow by 12 feet in a year, according to the International Aroid Society.