Polka dot plant cuttings root easily in a container filled with a well-drained potting mix. Although a homemade mixture consisting of equal parts peat moss and perlite is appropriate, a quality commercial potting mix works just as well. Moisten the potting mixture lightly, as the mixture should be damp but not soggy. You can mist the mixture with a spray bottle, or soak it thoroughly and then allow it to drain overnight. A pot with a drainage hole is critical for propagating any plant, as cuttings easily rot in poorly drained soil.
For best results, select a healthy stem from a polka dot plant that is actively growing. Cuttings from ailing or unhealthy plants aren't as likely to root; however, if your plant appears to be dying, you may be able to start a new plant from the healthiest stem. Cut a length of stem measuring 1 to 3 inches long, with at least two or three leaves, and then pull one or two of the leaves from the bottom half of the stem. Although rooting hormone isn't required, dipping the bottom 1 inch of stem in rooting powder increases the chance that the stem takes root.
To plant a polka dot stem cutting, insert the bare end of the stem in the moist potting soil. Ensure that at least one of the leaf nodes -- the spot where you pulled the leaf from the stem -- is in the potting mix. This is critical, because roots develop from the nodes. Firm the potting mix lightly around the stem. To create a miniature greenhouse, slide the container into a clear plastic bag, and then close the top of the bag with a rubber band.
Stem cuttings benefit from the humid environment inside the plastic bag. Although the cuttings require sunlight, avoid sunny windowsills, which may be hot enough to scorch the cuttings. An occasional misting inside the bag is usually enough to keep the environment damp, but if drips of condensation build up inside the bag, poke a few holes in the plastic or open the top of the bag. Cuttings usually root in about two weeks, depending on the temperatures.
Polka dot stem cuttings continue to benefit from the warm, humid environment in the plastic bag until healthy new growth is apparent, which indicates that the cuttings are rooted. At that time, open the top of the bag for a few days so the plant has time to acclimate to the cooler air. Remove the bag, and then move the plant into brighter light. Continue to keep the soil lightly moist.