Choose two cucumber plants to graft. Plant the main cucumber plant or rootstock in a 4-inch pot with damp potting soil. The second plant, or scion, will be grafted to the main rootstock and does not require special potting.
Pinch-off the first true leaf from the rootstock using your fingers. Grip the leaf stem at the point where it meets the main stem and pinch to remove.
Slice one cotyledon from the rootstock at a 45-degree angle using a razor blade. Perform the same cut on the scion, this time making the 45-degree-angle cut just below the embryo.
Press the exposed tissue of the scion against that of the rootstock. Clamp the stems together using a grafting clip.
Mist the grafted cucumber plants with water from a spray bottle to moisten. Place the pot in filtered sunlight and continue to maintain moist soil as the graft mends.
Check the graft every few days. Remove the grafting clip when the union between the two plants heals.