Watch the rose bush's new growth and buds for any signs of an aphid infestation. The small insects usually cluster along the plant's stems and leaves, and a heavy infestation of the pests encompass the buds.
Hose the aphids from the rose bush using a strong burst of water from the hose. The water dislodges the pests, washing away the adult insects, nymphs and eggs. Combine water with insecticidal soap or neem oil to effectively kill all the aphids and prevent reinfestation. Follow the application directions on the insecticidal soap or neem oil. Monitor the rose bush carefully for any reinfestations.
Purchase ladybugs from a garden center. Ladybugs are a natural predator of aphids. Release the newly purchased ladybugs onto the rose bush in the evening.