Barberry has been used for more than 2,500 years in folk medicine. This herb was used to treat diarrhea, fever, loss of appetite, stomach upset and loss of vigor.
Oregon grape root is a traditional oral and topical folk medicine. It was used for skin problems, gastritis, fever, hemorrhaging, jaundice, gall bladder disease and cancer.
Barberry is used to ease inflammation and infection of urinary tracts. It is also used to treat sore throats, nasal congestion, sinusitis, bronchitis, psoriasis and diarrhea.
Oregon grape root is used as a topical ointment. It may reduce symptoms of psoriasis, athlete's foot, eczema and acne.
Berberine causes uterine contractions and can lead to a miscarriage in pregnant women. Neither barberry nor Oregon grape root is safe for internal use by young children, nursing women, people with severe liver disease and people with kidney disease. These herbs may interact with antibiotics, blood thinners, antihistamines, blood pressure medicines, water pills and diabetic medicines.