Grapes won't thrive in the wrong planting sites, regardless of soil or fertilizer. Plant grapevines in spots with full sun for eight hours every day, quick drainage, good air circulation and at least 10 to 15 feet of space per planting site. Plant grapevines in spring in any growing zone to allow a summer of growth and establishment.
Successful grape growth starts with healthy, nutritious soil. Purdue University notes that grapevines produce their best root systems in loose, airy, quick-draining and fertile soil. Turn over the top 12 to 24 inches of soil in each planting site and add 6 to 12 inches of organic compost to provide this foundation. Compost loosens the soil and retains moisture for healthy growing.
The Ohio State University Extension notes that grapes do best with a slightly acidic pH at 5.0 to 6.0. The Extension recommends giving new grapes 10-10-10 granular fertilizer one week after planting, at a rate of 8 oz. of fertilizer per plant. Sprinkle the fertilizer in a circle 8 to 12 inches from the trunk of the grapevine, and mix it into the top 3 inches of soil. Always water grapevines after you feed them.
Fertilize grapes again every spring, before new growth appears. Give each grapevine 1 lb. of 10-10-10 fertilizer in the second year of growth, and 1 1/2 lbs. of fertilizer every year thereafter. Mix 3 inches of organic compost into the soil at the same time, to maintain good soil quality through the growing season.