Grow gloxinia plants inside draining containers that are at least 5 inches in size or larger, according to Colorado State University Extension. Allow the tubers adequate space for proper growth by growing the plant in a container that does not force crowding of the tubers.
Fill the container two-thirds full with a lightweight potting mix or create your own mixture. Mix one-third perlite, one-third compost and one-third peat moss together and fill the container one-third full of the soil mixture. Place the tuber on top of the soil, rounded side down, and cover with soil.
Water the gloxinia tuber after planting, saturating the soil. Place a saucer underneath the container and fill it with water two to three times weekly. Pouring water over the plant sometimes causes crown rot, as the plant is sensitive to excessive water amounts.
Fertilize gloxinia plants with an all-purpose houseplant fertilizer once the tubers sprout, following package directions. Fertilize actively growing and blooming plants every three weeks. Apply the fertilizer the same way you water the plant by pouring it into the bottom saucer.
Place the gloxinia container in an area receiving bright, indirect light during the warmer seasons of spring and summer. Situate the container near a south- or west-facing window throughout winter, as the plant withstands more sunshine during the cool, winter months.
Fill a plastic spray bottle with water. Mist the gloxinia plants weekly to create humidity, as plants perform best in humid environments.