Check for maturity beginning in mid-fall, depending on the area of the country you are in. The pears typically are ready to harvest in late September or early October. Mature Comice pears develop a red blush as they approach harvest time.
Grasp a pear by its bottom. Lift the pear toward the branch and twist lightly. The pear separates easily from the branch if it's ready to harvest. Check multiple pears and harvest all of them if most separate easily.
Stack the pears in a single layer in a shallow box. Use a box with holes in the sides to allow air to circulate.
Store the boxes in a location that's 32 to 45 degrees Fahrenheit. Stack multiple boxes crosswise so air can enter the top of the boxes at the bottom of the stack.
Keep the pears in cold storage for two to four weeks. Check for ripeness weekly by pressing lightly against the top of the pear near the stem. The pears are ready to eat when this area feels soft.