Plant the prickly pear cactus an area with sandy soil where it can get full sun.
Water the nopales only when the soil is very dry and during periods of extreme drought.
Fertilize the nopales only if you aren't growing the paddles for food. Fertilizer causes the paddles to grow larger, which is an undesirable trait for eating but may be desirable for ornamental purposes. Apply a 10-10-10 fertilizer, at the rate suggested on the fertilizer label, in the spring.