Viruses represent a common problem in blackberries, according to the National Gardening Association. Symptoms include yellowing leaves and general failure to thrive. No treatment exists for viruses, so consider using only nursery transplants certified as virus-free to avoid this problem.
Additional diseases afflicting blackberry vines originate from various fungi, with the exception of crown gall, a bacterial disease. Leaf spot, double blossom and anthracnose weaken the plant, infecting foliage, stems or buds, and may be ultimately deadly to the plant.
Blackberry vines are often attacked by insects, including raspberry crown borers, the strawberry weevil and aphids. Serious infestations require insecticide applications, but occasional problems may not warrant such action, depending on pest problems in your local area.
Weeds present problems in any landscape, but those near blackberry vines are especially problematic because of the shallow roots of blackberries. Mulches such as plastic or pine bark help prevent weed problems and the need to hoe, which easily injures blackberry roots. Consider herbicide use to combat weeds as well.