Harvest Pyracantha berries late in the autumn but before the first frost. The red berries are more appetizing than the golden varieties. Do not pick green, unripe berries.
Put on a pair of thick gardening gloves. The Pyracantha bush contains many thorns that will dig deep into unprotected skin. Make sure your arms are covered with long sleeves.
Gently pull the bright red berries off of their stems. Remove large clusters at a time, if you prefer, with gardening clippers. You can pick through the berries later and remove all of the stems.
Make jam or jelly from the Pyracantha berries. Do not eat the berries raw, as they are very bitter. These berries also may be mildly toxic until cooked.