Collect cleome seed pods after the blossoms have gone to seed. Split the pods open and save the inside seeds in a paper envelope. Store the seeds in a dry location for planting the following spring.
Place the seeds in the refrigerator approximately one week prior to planting.
Choose a planting location that has well draining soil and full sun to partial shade light conditions.
Loosen the soil in the flower bed where the seeds will be planted in spring once there is no longer a danger of frost. Work compost into the soil to increase the nutrient value and moisture retention. Rake the area smooth.
Sow the seeds in the soil by scattering several seeds in each planting area set at a distance of 12 inches apart. Gently cover the seeds with ¼-inch of soil and pack lightly.
Water the soil after planting to moisten without making it wet. Continue to water the seed area during germination to prevent the soil from drying out.
Pinch off seedlings that are growing on top of each other to prevent root competition from plants growing too close together.