Water creeping wire vine about once every week, as the plant prefers moist, but not drenched soil. Water deeply, saturating the soil to a depth of about 6 inches, and then allow the top 1 inch of the soil to dry before the next watering.
Pull or hoe weeds that grow around newly planted vines as soon as they appear because weeds compete with the plants for moisture and soil nutrients. Weeds are usually not an issue once the vines are established.
Spread a 2-inch layer of mulch around new plants to keep the soil moist and keep weeds in check. Use an organic mulch such as shredded bark or peat moss.
Fertilize creeping wire vine yearly, in spring or late fall. Use a general purpose, dry fertilizer with a balanced ratio, such as 10-10-10. Apply the fertilizer at a rate of 1 1/2 to 2 pounds for every 100 square feet of planting space.
Trim creeping wire vine as needed to maintain a neat appearance, using pruners, a weed trimmer or a mower set on high. The vine rebounds quickly.