Wear garden gloves when working with weeds. Pull young weeds from the base, gently and slowly tugging to avoid breaking the stems. If you pull correctly, you will pull out the whole root, eliminating the weed. Pulling weeds is only effective if you can pull the whole root and stop the weed from dropping new seeds.
Spray herbicide glyphosate onto broken or exposed weed stems. If the weeds are full, trim the heads off to expose the stems, and then treat with glyphosate. The herbicide kills weeds and absorbs into exposed stem or root material more quickly and effectively .
Fill a spray bottle or garden sprayer with boiling hot water. Spray the hot water carefully and precisely into all of the joints in the concrete slab. The boiling water will cook all weeds and most weed seeds, stopping future weed growth.
Repeat application of glyphosate or boiling water as needed if more weeds appear. You can also treat the slabs with either water or the chemical every two to three weeks to prevent new weeds from starting.