Dig up any tubers and rhizomes with a spade in late June before new tubers begin to form. Gather all the tubers in a basket and put them in the yard waste container if you have a small garden.
Till the field two or three times if the Jerusalem artichokes have become weeds in larger gardens or farms. You should till the field in late June to get rid of new tubers.
Use the mower to remove the top growth frequently to prevent Jerusalem artichoke tubers and rhizomes from spreading.
Apply herbicide with a sprayer from midsummer to late autumn to get rid of Jerusalem artichoke rhizomes and tubers. Spray as soon as the plants reach a height of 8 to 12 inches. Spray again 10 days after the first application. Effective brand names of herbicides that treat Jerusalem artichokes include Kilmor, manufactured by Ciba-Geigy, Banvel by Sandoz and Roundup by Monsanto.
Wear rubber gloves and try to find roots and rhizomes of Jerusalem artichokes with your hands. Remove all of the growth that you find manually or with a garden fork and put it out for garbage collection.