Lay a paper towel over the greasy spill on the leather. Absorb any excess grease from the surface then discard the towel.
Cover the grease stain on your leather item with talcum powder to absorb the remaining grease. Leave the powder on the leather surface for 20 minutes.
Brush off the leather surface with a clean cloth to remove the talcum powder. Sweep the powder into the trash. Repeat Steps 2 and 3 if the greasy spot still remains on the leather.
Dampen a clean cloth with white vinegar. Squeeze out the excess liquid.
Dab at the leather surface to remove any last traces of grease, as well as to clean and deodorize the material. Dry the leather with another cloth.
Pour a nickel-sized amount of leather conditioner onto a cloth. Rub the conditioner into the leather to restore the leather's moisture.