Read the label. Note whether it says "dry clean only" on the label and what the fabric is. Silk and wool products should be taken to the dry cleaner, though some other fabrics may state dry clean if there is a lot of intricate detail and stitching. You can clean these, though you should do so with caution.
Beat the pillows gently outside to remove much of the dust that settles on the pillows over time.
Vacuum the pillows with the low setting on the vacuum, using the small detail attachment to control the areas of suction. Be careful around embroidery or other attached decorations to prevent pulling them up.
Throw the pillows in the dryer on a "no heat" setting with a fabric softener sheet for 20 minutes. This fluffs the pillows and freshens them.
Remove pillow covers that are removable and pre-treat any stains with stain remover. Wash by hand or on a delicate cycle before either air drying or delicate drying in the dryer.
Clean stains on pillows without removable pillow cases by blotting the stain with stain remover. Let the stain remover sit for 10 minutes before you blot the area with clean water. Allow the pillow to air dry thoroughly to prevent mold or mildew growth. Place the pillow in the dryer on "no heat" to fluff after cleaning.