Put a clean garment into the dryer, to let the heat remove wrinkles. Do not dry the item if it has any stains, because the heat will set them further. And don't machine dry an item if it's not recommended on the care label.
Hang the garment in the bathroom while you take a hot shower. The heat and steam cause fibers to relax and wrinkles to smooth out. You can also use a steamer, following the manufacturer's directions, to remove wrinkles in a similar fashion.
Blast the garment with a blow dryer set on high heat. Keep heat on the fabric while constantly moving the dryer to prevent burns. Use your hand to lightly tug the fabric while drying, to encourage the fabric to relax.
Spray the item lightly with a wrinkle relaxing spray, following the manufacturer's directions. Be sure to check the label of your garment before using any chemicals on the fabric.
Spray clothing that cannot handle chemical sprays with warm water. Gently tug the fabric at the base to release wrinkles, and allow it to air dry.
Iron stubborn wrinkles by laying the item flat and inside out on an ironing board. Set the iron to a medium setting, and allow it to heat up fully.
Steam the fabric just before ironing it, by spraying it with warm water using a water bottle or the steam setting on your iron. Iron over the fabric slowly to release the wrinkles.
Move the fabric, and spray it with warm water. Iron the section of fabric. Continue until the entire garment has been ironed.