Clean all stains from the surface of your mattress using a sponge and a spray solution of 50 percent white vinegar and 50 percent water. Do not saturate the mattress.
Arrange four or more cinder blocks or large stones on the ground outside as a foundation for your mattress.
Take your mattress outdoors and place the mattress right-side-up on top of the blocks or stones. Allow the mattress to air dry in the sun. The blocks or stones allow air to circulate underneath the mattress.
Place a fan by your mattress and allow air to blow directly on it, if you need to dry the mattress more quickly.
Return the completely dry mattress to the bedroom. If your mattress became wet due to flooding, the Centers for Disease Control and Prevention (CDC) suggests that you spray the mattress thoroughly using a disinfectant after allowing it to air dry.