Blot fresh urine off the leather furniture using several paper towels until no more urine can be absorbed.
Dampen a lint-free cloth with cool water. Wipe the leather furniture with the cloth. Allow the leather to air dry. Continue with the remaining steps if the odor persists.
Fill a small container with equal parts cool water and white vinegar. Dampen a clean, lint-free cloth in the mixture.
Wipe the leather furniture with the damp cloth. Vinegar is an all-natural cleaner and deodorizer that will remove tough odors such as urine. Allow the vinegar to sit on the leather for 10 minutes.
Wipe the leather clean with a damp cloth. Remove excess moisture from the leather by wiping with a towel. Allow the leather to air dry.
Apply a leather cleaning and conditioner to a clean, lint-free cloth. Buff the leather furniture with the damp cloth. Allow to air dry.