Locate the leak by taping the end of a duct blower to a vent that accesses the duct system. The blower shoots air into the duct so you can locate the leaks in the system.
Seal cracks or slits in the duct by attaching metal tape over them. Avoid using duct tape; the adhesive is weaker than on metal tape and doesn't last. Metal tape is stronger and prevents air from escaping through the leak.
Wrap insulation around the areas of duct work where leaks were discovered, This further helps prevent heat from escaping.