Remove the screws from the doorknob, and take the doorknob down from the door. Set the screws aside in a safe place.
Dampen a cloth, and use it to wipe the doorknob, removing all dirt and grime.
Remove the old lacquer finish if it is present. Dip a paintbrush into an acetone-based lacquer thinner, and apply the thinner evenly over the doorknob. Rub the doorknob with a clean cloth.
Stir the lacquer if the manufacturer recommends stirring the product. Place the doorknob on newspaper to protect your work area's surface.
Dip a clean polyester brush into the lacquer, and apply a thin, even coat of lacquer on the doorknob.
Allow the coat of lacquer to dry completely. The drying time depends on the specific product; follow the manufacturer's directions.
Apply an additional two to four coats of lacquer, or as many coats as the lacquer manufacturer recommends. Let each coat dry completely before applying a new coat. Allow the doorknob to dry before reinstalling it on the door.