Hold one end of the duct hanger strap up to the side of a structural member above the flex duct. Fasten the hanger strap to the structural member with two screws. The second screw allows for extra support. Avoid screwing to the bottom of a structural member, if possible, as a screw is more likely to pull straight out than shear off.
Hold the flex duct at the desired elevation and wrap the hanger strap around it. Pull the strap up to the structural member and make a mark where you need to cut it.
Cut through the hanger strap at the mark with your snips. Screw it to the structural member with at least two screws. If correctly done, the strap will take on a "U" shape with the flex duct resting in the cradle of the "U."
Repeat Steps 1 through 3 to support the flex duct at least every 5 feet.