Measure the length from the dropped ceiling grid to the height from which you want the picture to hang. Add 6 inches to this number and cut two pieces of airplane wire of that length.
Stand on a ladder as someone spots you for safety. Gently push the ceiling tile up and thread one of the wires over a piece of the ceiling grid. Fold the top 3 inches of the wire over and secure it to the other section of wire with a wire rope clip. Repeat the process with the other piece of wire. Space the two wires apart at the width of your picture frame.
Screw two eye hooks on opposite sides of your picture frame. Thread one hanging wire through each eye hook. Fold 3 inches over and secure into place with a rope clip to complete the hanging process.