Screw a single eyehook at the top center of your picture frame. Use a drill to create a starter hole for easier installation if necessary.
Locate a stud in your ceiling in the area where you plan to hang the picture. Mark the spot with a small pencil mark.
Drill a pilot hole into the ceiling and stud. Screw an eyehook into place.
Measure down from the ceiling eyehook to the point where you want the top of the picture. Add 6 inches to the measurement and cut a piece of high-tension airplane wire to that length.
Thread the high-tension airplane wire through the ceiling eyehook and fold it over 3 inches. Snap a wire rope clip into place to secure the wire. Repeat the threading and securing process on the eyehook of the picture frame to complete the hanging.