Check the HEPA Airwatch indicator. Your installer will likely have placed it near the thermostat. Look for a cigarette pack-sized box. It will be marked Honeywell Airwatch. The indicator will display an arrow next to any filters that need replacing.
Perform a visual inspection of the filters. Replace the filters if they are plugged.
Make sure the filters are installed correctly. There are air flow direction arrows on the pre-filter and HEPA filter.
Make sure the filters are installed in their correct locations. The locations and the filters are marked. Make sure they match.
Check the ductwork if you experience poor air flow and the filters are clean. Make sure all the vents are open.
Check the filters for dirt if the unit becomes noisy or the filter change light comes on.
Wash the pre-filter. The main filter is not washable---it needs replacing.
Check that the protective wrap is removed from the new filter before installing it.
Make sure you have proper airflow. The unit should be located at least 3 feet from any wall or furniture.