Place one crimp on one end of wire, about 1 inch from the end. Loop the end of the beading wire through one end of the clasp, and thread it back through the crimp, pushing the crimp as far up as possible to create a firm hold. Flatten the crimp with the pliers.
Thread on one Cleopatra bead, pushing it close to the crimp. Follow it with one round bead.
Continue alternating Cleopatra beads with the small round beads, until the wire has 6 inches left in it. You can also fill it until it only has 2 inches left at the end to create a larger necklace.
Thread a crimp bead onto the open end of the necklace. Thread the other half of the clasp on as well.
Maneuver the end of the wire back through the crimp bead. Pull it tightly so the beads are snug between each clasp. Flatten the crimp with the pliers, and cut off any excess wire with the cutters.