Water the area of lawn that contains foxtail until the soil is thoroughly wet. Continue to irrigate the area until the foxtail grows noticeably taller. Glyphosate, an herbicide, only works on foxtail plants that are active.
Mix 1.25 ounces of glyphosate herbicide with 1 gallon of water. Use 25 gallons of this mixture for every acre affected by knotroot foxtail.
Spray the affected area with the glyphosate mixture.
Wait about one to two weeks for the foxtail to die. Use a garden hoe or similar tool to dig up the dead foxtail and to either remove it or turn it under the soil.
Water the affected area until the soil is wet. Wait about another two weeks for any foxtail seeds left in the soil to germinate and grow. Reapply the glyphosate.