Clean Room Design Requirements

Building Material Requirements

• Building materials used to create a clean room must not be porous or made from organic matter like wood. Aluminum, stainless steel and other metals that do not degrade over time should be utilized in the construction of a clean room. Building materials may vary by the room's space cleanliness classification, according to the CBS Interactive Business Network. Clean rooms are also required to incorporate bacteria resistant building materials like mylar for ceiling and wall construction.

Space Pressurization

• In order to maintain space pressurization in a clean room, it is required to have only one entrance. This entrance must be built with a sterile air-lock that maintains the positive pressurization within the clean room, according to the CBS Interactive Business Network's "Cleanroom Design in 10 Easy Steps." This ensures that any air filtrating into the clean room is coming from an area with the same pressurization standard. The room is required to be air tight in all respects with air pumped in through a dedicated filtration system.

Air Filtration System

• A clean room is only as good as its air filtration system. The system is required to be rated to eliminate particles within the clean room's air supply consistent with the room's space cleanliness classification, according to the education and environmental engineering website PDH Online. For example, the air filtration system for a Class 100 clean room is required to eliminate airborne particles equal to or greater than 0.5 microns to 100 particles in a cubic foot of air. The active supply, control and exhaust systems for the air control devices used in the clean room are required to have a minimum of 10 percent difference between them. This to remove any static charge that can build up from system operation and cause diminished functionality. A malfunctioning air filtration system can lead to increased heat which could encourage moisture buildup. Moisture leads to bacterial growth and a compromised clean room.