Start nailing at the left corner of the edge of the floor opposite the door. Install a row of nails that are 6 inches apart and 3/8-inch from the panel's edge. Start the first nail 3/8-inch in from the leftmost edge of the plywood flooring panel. Continue nailing all around the perimeter of the floor.
Return to the starting corner. Space nails over the rest of the floor in a grid-like pattern. Install each nail 6 inches apart from neighboring nails on all sides. Shift the spacing slightly, when necessary, to install the nails 3 inches from the edge of each panel.
Go back over the floor to check the nailing depth of the subfloor. Each nail should be flush with or just below the surface of the plywood. If the nails are too deep, those low points may be visible in the flooring layer. If the nails are not driven deeply enough, the high points will show through the flooring layer. Hammer down under-driven nails and remove then re-install over-driven nails.